Summary: All children are susceptible to SARS-CoV-2 infection, which causes COVID-19, although they usually suffer from it milder than adults. The vast majority of children recover within 4 to 12 weeks; a small percentage report various symptoms for many months, including fatigue, muscle and joint pain, headache, dyspnea, chest pain, cognitive impairment, insomnia, palpitations, nausea, and dizziness. Results of prospective studies with a control group indicate that the percentage of children with long-term sequelae of COVID-19 may be as high as several percent. The lack of differences between groups regarding psychosomatic symptoms, with differences in somatic symptoms, demonstrates that long COVID of children and adolescents is a viable health disorder. The best way to avoid COVID-19 complications is to prevent SARS-CoV-2 infection by distancing, masks, ventilation, hand hygiene, and immunization. Long COVID should be considered a negative consequence of SARS-CoV-2 infection when making decisions regarding COVID-19 vaccination of children.