Summary: Muco-active agents are frequently administered in airway infection treatment. This approach also applies to patients with coronavirus pneumonia. Erdosteine seems to be a multifaced agent with beneficial properties used in airway disease treatment. It is used in COVID-19 patients, but also helps in the recovery and pulmonary rehabilitation of COVID-19 survivors. In this review we describe erdosteineʼs role in the latter, based on current literature.