Summary: Cannabinoids are increasingly used as a therapeutic option in the treatment of pain. Due to their unique, multidirectional mechanisms of action, cannabinoids are finding wider and wider application in the treatment of many diseases, especially where other drugs do not show optimal efficacy or their action is associated with the occurrence of side effects. The availability of an increasing number of products containing cannabinoids should provide an opportunity to become familiar with the practical aspects of using this group of analgesics.