Summary: Allergic rhinitis (AR) is one of the most common allergic diseases in the world – about 1/4 of the European population suffers from AR. The most typical symptoms of AR are sneezing, clear rhinorrhea, itching and nasal blockade, furthermore, ear, throat and ocular symptoms are frequently observed. Pathophysiology of AR is directly related to mast cell degranulation, which depends on the production of IgE antibodies in the course of an exposure to a specific allergen. The most common allergens associated with perennial AR are house dust mites. On the other hand, allergens predominantly associated with seasonal AR are pollens. Diagnosis of AR is based on detailed patient history, skin prick tests, as well as serum IgE levels. Standardized questionnaires are also helpful at the time of diagnosis, as well as during follow-up examinations. Pharmacotherapy is based on oral and intranasal antihistamines, intranasal corticosteroids, their combination preparations, as well as saline solutions. The singular causative intervention is the allergen immunotherapy. Although the treatment of AR has not changed fundamentally over the years, it is the subject of constant comprehensive research, including the therapeutic potential of drugs that have not been used in allergic rhinitis so far.