Summary: Introduction: Efficient cooperation between medical and paramedical staff is becoming increasingly important in the face of challenges such as staff shortages, an aging society, and growing demand for healthcare services. An optimally functioning healthcare system model helps reduce the negative effects of so-called “medical deserts”. One mechanism for the effective use of human resources is the “skill-mix” concept, the aim of which is to adapt the professional roles of medical staff through their modification, extension, or substitution. Methodology: The aim of the study was to analyse national and international experiences related to the implementation of the “skill-mix” model and to identify solutions that could be adapted to Polish conditions, enabling support for healthcare within a coordinated model. The research methodology was based on analysis of the available literature using two electronic databases (PubMed and Scopus). Results: Adjusting professional roles and transferring some responsibilities between professions allows doctors to focus on more demanding cases. International solutions include expanded competencies for pharmacists in Great Britain, direct referral of patients to physiotherapists in France, and the involvement of auxiliary staff, such as assistants. In Poland, attempts to implement this model include granting nurses and physiotherapists the status of independent professions, as well as introducing new entitlements for pharmacists and paramedics. However, the introduction of new roles is associated with challenges, such as imprecise definitions of competencies or resistance from existing staff. Summary: The introduction of new professional roles leads to improved access to healthcare. It also contributes to reduced costs and increased profitability of medical facilities. To ensure the effective implementation of these changes, simultaneous action in the legislative, organizational, and educational domains is necessary.